ITGB5 Antibody

ProSci
Product Code: PSI-57-409
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-409-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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ITGB5 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
ITGB5 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Integrin beta-5, ITGB5
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Li, Z., et al. J. Biol. Chem. 285(31):23699-23710(2010)
  • Leifheit-Nestler, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(7):1398-1406(2010)
  • Lane, D., et al. Oncogene 29(24):3519-3531(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This ITGB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-244 amino acids from the N-terminal region of human ITGB5.
NCBI Gene ID #:
3693
NCBI Official Name:
Integrin beta-5
NCBI Official Symbol:
ITGB5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
P18084
Protein GI Number:
124970
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P18084
User NOte:
Optimal dilutions for each application to be determined by the researcher.