PHACTR3 Antibody
Code | Size | Price |
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PSI-56-682-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Phosphatase and actin regulator 3, Scaffold-associated PP1-inhibiting protein, Scapinin, PHACTR3, C20orf101, SCAPIN1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is associated with the
nuclear scaffold in proliferating cells. It was found to bind to
the catalytic subunit of protein phosphatase-1 (PP1) and inhibit
PP1 activity, suggesting that this protein may function as a
regulatory subunit of PP1. Alternative splicing at this locus
results in several transcript variants encoding different isoforms.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Bankovic, J., et al. Lung Cancer 67(2):151-159(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PHACTR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human PHACTR3.
NCBI Gene ID #:
116154
NCBI Official Name:
Phosphatase and actin regulator 3
NCBI Official Symbol:
PHACTR3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
Q96KR7
Protein GI Number:
38605426
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96KR7
User NOte:
Optimal dilutions for each application to be determined by the researcher.