MAT1A Antibody
| Code | Size | Price |
|---|
| PSI-56-593-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
S-adenosylmethionine synthase isoform type-1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1, Methionine adenosyltransferase I/III, MAT-I/III, MAT1A, AMS1, MATA1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene catalyzes a two-step reaction that involves the
transfer of the adenosyl moiety of ATP to methionine to form
S-adenosylmethionine and tripolyphosphate, which is subsequently
cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl
groups for most biological methylations. The encoded protein is
found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a
third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations
in this gene are associated with methionine adenosyltransferase
deficiency.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Wu, S.M., et al. Cell. Mol. Life Sci. 67(11):1831-1843(2010)
- Lai, C.Q., et al. Am. J. Clin. Nutr. 91(5):1377-1386(2010)
- Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Bovine
Immunogen:
This MAT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the N-terminal region of human MAT1A.
NCBI Gene ID #:
4143
NCBI Official Name:
S-adenosylmethionine synthase isoform type-1
NCBI Official Symbol:
MAT1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q00266
Protein GI Number:
417297
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q00266
User NOte:
Optimal dilutions for each application to be determined by the researcher.