FGD6 Antibody

ProSci
Product Code: PSI-55-633
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-633-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).
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FGD6 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in A549 cell line lysates (35ug/lane).
FGD6 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
FYVE, RhoGEF and PH domain-containing protein 6, Zinc finger FYVE domain-containing protein 24, FGD6, KIAA1362, ZFYVE24
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
Background References:
  • Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
  • Jin, J., et al. Curr. Biol. 14(16):1436-1450(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FGD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1324-1352 amino acids from the C-terminal region of human FGD6.
NCBI Gene ID #:
55785
NCBI Official Name:
FYVE, RhoGEF and PH domain-containing protein 6
NCBI Official Symbol:
FGD6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
161 kDa
Protein Accession #:
Q6ZV73
Protein GI Number:
61213484
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q6ZV73
User NOte:
Optimal dilutions for each application to be determined by the researcher.