SNX3 Antibody

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ProSci
Product Code: PSI-59-911
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-911-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Immunohistochemical analysis of paraffin-embedded H. kideny section using SNX3 Antibody . Antibody was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
2 / 4
Western blot analysis of lysates from A431, THP-1 cell line and mouse spleen tissue lysate (from left to right), using SNX3 Antibody at 1:1000 at each lane.
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4 / 4
Western blot analysis in A2058 cell line lysates (35ug/lane).
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Immunohistochemical analysis of paraffin-embedded H. kideny section using SNX3 Antibody . Antibody was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Western blot analysis of lysates from A431, THP-1 cell line and mouse spleen tissue lysate (from left to right), using SNX3 Antibody at 1:1000 at each lane.
Western blot analysis in A2058 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Sorting nexin-3, Protein SDP3, SNX3
Application Note:
For IHC-P starting dilution is: 1:25

For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking.
Background References:
  • Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
  • Pons, V., et al. PLoS Biol.(9), E214 (2008) :
  • Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
  • Dong, H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 39(7):540-546(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Immunogen:
This SNX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-105 amino acids from the Central region of human SNX3.
NCBI Gene ID #:
8724
NCBI Official Name:
Sorting nexin-3
NCBI Official Symbol:
SNX3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
O60493
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O60493
User NOte:
Optimal dilutions for each application to be determined by the researcher.