XPOT Antibody

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ProSci
Product Code: PSI-63-074
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-074-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of XPOT antibody in Ramos cell line lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human lymph with XPOT Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of XPOT antibody in Ramos cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human lymph with XPOT Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Documents

Further Information

Additional Names:
Exportin-T, Exportin(tRNA), tRNA exportin, XPOT
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
XPOT is a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.
Background References:
  • Li,S.RNA Biol(4), 145-149 (2006)
  • Suzuki,T., Biomed. Res. 27 (2), 89-92 (2006)
  • Kuersten,S., Mol. Cell. Biol. 22 (16), 5708-5720 (2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This XPOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the N-terminal region of human XPOT.
NCBI Gene ID #:
11260
NCBI Official Name:
Exportin-T
NCBI Official Symbol:
XPOT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
O43592
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
O43592
User NOte:
Optimal dilutions for each application to be determined by the researcher.