IHH Antibody
Code | Size | Price |
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PSI-58-107-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Indian hedgehog protein, IHH, HHG-2, Indian hedgehog protein N-product, Indian hedgehog protein C-product, IHH
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the hedgehog family of
secreted signaling molecules. Hedgehog proteins are essential
regulators of a variety of developmental processes including
growth, patterning and morphogenesis. The encoded protein
specifically plays a role in bone growth an differentiation.
Mutations in this gene are the cause of brachydactyly type A1 which
is characterized by shortening or malformation of the phalanges.
Mutations in this gene are also the cause of acrocapitofemoral
dysplasia.
Background References:
- Meulenbelt, I., et al. Ann. Rheum. Dis. (2010) In press :
- Kang, S.J., et al. Hum. Mol. Genet. 19(13):2725-2738(2010)
- Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)
- Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This IHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human IHH.
NCBI Gene ID #:
3549
NCBI Official Name:
Indian hedgehog protein
NCBI Official Symbol:
IHH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q14623
Protein GI Number:
33112634
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q14623
User NOte:
Optimal dilutions for each application to be determined by the researcher.