HCLS1 Antibody

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ProSci
Product Code: PSI-57-433
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-433-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysates from K562, Raji cell line (from left to right), using HCLS1 Antibody at 1:1000 at each lane.
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
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Western blot analysis of lysates from K562, Raji cell line (from left to right), using HCLS1 Antibody at 1:1000 at each lane.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75, HCLS1, HS1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Background References:
  • Muzio, M., et al. Leukemia 21(9):2067-2070(2007)
  • Lim, J., et al. Cell 125(4):801-814(2006)
  • Hao, J.J., et al. J. Biol. Chem. 280(45):37988-37994(2005)
  • Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HCLS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 362-391 amino acids from the C-terminal region of human HCLS1.
NCBI Gene ID #:
3059
NCBI Official Name:
Hematopoietic lineage cell-specific protein
NCBI Official Symbol:
HCLS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
P14317
Protein GI Number:
317373440
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P14317
User NOte:
Optimal dilutions for each application to be determined by the researcher.