HCCS Antibody
| Code | Size | Price |
|---|
| PSI-64-165-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cytochrome c-type heme lyase, CCHL, Holocytochrome c-type synthase, HCCS, CCHL
Application Note:
For WB starting dilution is: 1:4000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.
Background References:
- Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
- Wimplinger, I., et al. Mol. Vis. 13, 1475-1482 (2007)
- Wimplinger, I., et al. Am. J. Hum. Genet. 79(5):878-889(2006)
- Nakashima-Kamimura, N., et al. J. Cell. Sci. 118 (PT 22), 5357-5367 (2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken
Immunogen:
This HCCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-200 amino acids from the Central region of human HCCS.
NCBI Gene ID #:
3052
NCBI Official Name:
Cytochrome c-type heme lyase
NCBI Official Symbol:
HCCS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
P53701
Protein GI Number:
1705694
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P53701
User NOte:
Optimal dilutions for each application to be determined by the researcher.