HOXB3 Antibody
Code | Size | Price |
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PSI-56-515-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Homeobox protein Hox-B3, Homeobox protein Hox-27, Homeobox protein Hox-2G, HOXB3, HOX2G
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene is a member of the Antp homeobox family and
encodes a nuclear protein with a homeobox DNA-binding domain. It is
included in a cluster of homeobox B genes located on chromosome 17.
The encoded protein functions as a sequence-specific transcription
factor that is involved in development. Increased expression of
this gene is associated with a distinct biologic subset of acute
myeloid leukemia (AML).
Background References:
- Palakurthy, R.K., et al. Mol. Cell 36(2):219-230(2009)
- Ferrai, C., et al. Mol. Biol. Cell 20(15):3543-3551(2009)
- Chung, N., et al. Mol. Biol. Rep. 36(2):227-235(2009)
- Speleman, F., et al. Leukemia 19(3):358-366(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HOXB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human HOXB3.
NCBI Gene ID #:
3213
NCBI Official Name:
Homeobox protein Hox-B3
NCBI Official Symbol:
HOXB3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
P14651
Protein GI Number:
215274007
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P14651
User NOte:
Optimal dilutions for each application to be determined by the researcher.