HSD17B11 Antibody

ProSci
Product Code: PSI-64-124
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-64-124-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of HSD17B11 Antibody in WiDr cell line lysates (35ug/lane)
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HSD17B11 Antibody IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis of HSD17B11 Antibody in WiDr cell line lysates (35ug/lane)
HSD17B11 Antibody IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Estradiol 17-beta-dehydrogenase 11, 17-beta-hydroxysteroid dehydrogenase 11, 17-beta-HSD 11, 17bHSD11, 17betaHSD11, 17-beta-hydroxysteroid dehydrogenase XI, 17-beta-HSD XI, 17betaHSDXI, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, CTCL-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, Retinal short-chain dehydrogenase/reductase 2, retSDR2, HSD17B11, DHRS8, PAN1B
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones.
Background References:
  • Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009)
  • Nakamura, Y., et al. Neoplasma 56(4):317-320(2009)
  • Horiguchi, Y., et al. Arch. Biochem. Biophys. 479(2):121-130(2008)
  • Hartmann, T.B., et al. Br. J. Dermatol. 150(2):252-258(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This HSD17B11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human HSD17B11.
NCBI Gene ID #:
51170
NCBI Official Name:
Estradiol 17-beta-dehydrogenase 11
NCBI Official Symbol:
HSD17B11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q8NBQ5
Protein GI Number:
296439374
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8NBQ5
User NOte:
Optimal dilutions for each application to be determined by the researcher.