GDI2 Antibody
| Code | Size | Price |
|---|
| PSI-57-273-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2, GDI2, RABGDIB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
GDP dissociation inhibitors are proteins that regulate the
GDP-GTP exchange reaction of members of the rab family, small
GTP-binding proteins of the ras superfamily, that are involved in
vesicular trafficking of molecules between cellular organelles.
GDIs slow the rate of dissociation of GDP from rab proteins and
release GDP from membrane-bound rabs. GDI2 is ubiquitously
expressed. The GDI2 gene contains many repetitive elements
indicating that it may be prone to inversion/deletion
rearrangements. Alternative splicing results in multiple transcript
variants encoding distinct isoforms.
Background References:
- Rikova, K., et al. Cell 131(6):1190-1203(2007)
- Sun, Z.L., et al. Biochim. Biophys. Acta 1774(6):764-771(2007)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GDI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human GDI2.
NCBI Gene ID #:
2665
NCBI Official Name:
Rab GDP dissociation inhibitor beta
NCBI Official Symbol:
GDI2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
P50395
Protein GI Number:
13638228
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P50395
User NOte:
Optimal dilutions for each application to be determined by the researcher.