ACTN3 Antibody
| Code | Size | Price |
|---|
| PSI-56-350-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Alpha-actinin is an actin-binding protein with multiple
roles in different cell types. This gene expression is limited to
skeletal muscle. It is localized to the Z-disc and analogous dense
bodies, where it helps to anchor the myofibrillar actin filaments
Background References:
- Rodriguez-Romo, G., et al. Eur. J. Appl. Physiol. 110(6):1099-1106(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Berman, Y., et al. Physiology (Bethesda) 25(4):250-259(2010)
- Ruiz, J.R., et al. ScandMed Sci Sports (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ACTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-437 amino acids from the Central region of human ACTN3.
NCBI Gene ID #:
89
NCBI Official Name:
Alpha-actinin-3
NCBI Official Symbol:
ACTN3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
103 kDa
Protein Accession #:
Q08043
Protein GI Number:
215273967
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q08043
User NOte:
Optimal dilutions for each application to be determined by the researcher.