PTPRE Antibody
| Code | Size | Price |
|---|
| PSI-57-711-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon, PTPRE
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the
protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes
including cell growth, differentiation, mitotic cycle, and
oncogenic transformation. Two alternatively spliced transcript
variants of this gene have been reported, one of which encodes a
receptor-type PTP that possesses a short extracellular domain, a
single transmembrane region, and two tandem intracytoplasmic
catalytic domains; Another one encodes a PTP that contains a
distinct hydrophilic N-terminus, and thus represents a
nonreceptor-type isoform of this PTP. Studies of the similar gene
in mice suggested the regulatory roles of this PTP in RAS related
signal transduction pathways, cytokines induced SATA signaling, as
well as the activation of voltage-gated K+ channels. [provided by
RefSeq].
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
- Barr, A.J., et al. Cell 136(2):352-363(2009)
- Kraut-Cohen, J., et al. J. Biol. Chem. 283(8):4612-4621(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This PTPRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PTPRE.
NCBI Gene ID #:
5791
NCBI Official Name:
Receptor-type tyrosine-protein phosphatase epsilon
NCBI Official Symbol:
PTPRE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
81 kDa
Protein Accession #:
P23469
Protein GI Number:
126471
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P23469
User NOte:
Optimal dilutions for each application to be determined by the researcher.