FASTK Antibody
| Code | Size | Price |
|---|
| PSI-56-444-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Fas-activated serine/threonine kinase, FAST kinase, FASTK
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the
serine/threonine protein kinase family. This kinase was shown to be
activated rapidly during Fas-mediated apoptosis in Jurkat cells. In
response to Fas receptor ligation, it phosphorylates TIA1, an
apoptosis-promoting nuclear RNA-binding protein. The encoded
protein is a strong inducer of lymphocyte apoptosis. Two transcript
variants encoding different isoforms have been found for this gene.
Other variants exist, but their full-length natures have not yet
been determined.
Background References:
- Simarro, M., et al. J. Immunol. 184(9):5325-5332(2010)
- de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
- Simarro, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(27):11370-11375(2007)
- Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FASTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the C-terminal region of human FASTK.
NCBI Gene ID #:
10922
NCBI Official Name:
Fas-activated serine/threonine kinase
NCBI Official Symbol:
FASTK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
Q14296
Protein GI Number:
13124202
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q14296
User NOte:
Optimal dilutions for each application to be determined by the researcher.