ProSci

TESK2 Antibody

Product Code:
 
PSI-63-217
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western Blot at 1:500 dilution + HL-60 whole cell lysate Lysates/proteins at 20 ug per lane.
2 / 2
Formalin-fixed and paraffin-embedded human testis tissue reacted with TESK2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
❮❯

Western Blot at 1:500 dilution + HL-60 whole cell lysate Lysates/proteins at 20 ug per lane.
Formalin-fixed and paraffin-embedded human testis tissue reacted with TESK2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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PSI-63-217-400ul400ul£626.00
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Further Information

Additional Names:
Dual specificity testis-specific protein kinase 2, Testicular protein kinase 2, TESK2
Application Note:
For WB starting dilution is: 1:500

For IHC-P starting dilution is: 1:10~50
Background:
TESK2 is a dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. TESK2 phosphorylates cofilin at Ser-3. It may play an important role in spermatogenesis. This nuclear enzyme is thought to be activated by autophosphorylation on Ser-219. Expression is predominantly in testis and prostate, with highest concentrations in nongerminal Sertoli cells.
Background References:
  • Toshima,J.,J. Biol. Chem. 276 (33), 31449-31458 (2001)
  • Rosok,O., Genomics 61 (1), 44-54 (1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This TESK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the Central region of human TESK2.
NCBI Gene ID #:
10420
NCBI Official Name:
Dual specificity testis-specific protein kinase 2
NCBI Official Symbol:
TESK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa
Protein Accession #:
Q96S53
Protein GI Number:
25009462
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q96S53
User NOte:
Optimal dilutions for each application to be determined by the researcher.