KRT7 Antibody
Code | Size | Price |
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PSI-58-078-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7, KRT7, SCL
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the
keratin gene family. The type II cytokeratins consist of basic or
neutral proteins which are arranged in pairs of heterotypic keratin
chains coexpressed during differentiation of simple and stratified
epithelial tissues. This type II cytokeratin is specifically
expressed in the simple epithelia lining the cavities of the
internal organs and in the gland ducts and blood vessels. The genes
encoding the type II cytokeratins are clustered in a region of
chromosome 12q12-q13. Alternative splicing may result in several
transcript variants; however, not all variants have been fully
described.
Background References:
- Tsai, Y.Y., et al. Acta Derm. Venereol. 90(4):438-439(2010)
- Stewart, C.J., et al. Histopathology 57(1):46-54(2010)
- Nagashio, R., et al. Pathol. Int. 60(2):71-77(2010)
- Sano, M., et al. Int. J. Oncol. 36(2):321-330(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KRT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human KRT7.
NCBI Gene ID #:
3855
NCBI Official Name:
Keratin, type II cytoskeletal 7
NCBI Official Symbol:
KRT7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
P08729
Protein GI Number:
317373583
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P08729
User NOte:
Optimal dilutions for each application to be determined by the researcher.