RGS5 Antibody
Code | Size | Price |
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PSI-58-079-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Regulator of G-protein signaling 5, RGS5, RGS5
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the regulators of G protein
signaling (RGS) family. The RGS proteins are signal transduction
molecules which are involved in the regulation of heterotrimeric G
proteins by acting as GTPase activators. This gene is a
hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is
involved in the induction of endothelial apoptosis. This gene is
also one of three genes on chromosome 1q contributing to elevated
blood pressure. Alternatively spliced transcript variants encoding
different isoforms have been identified.
Background References:
- Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
- Li, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13818-13823(2010)
- Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RGS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human RGS5.
NCBI Gene ID #:
8490
NCBI Official Name:
Regulator of G-protein signaling 5
NCBI Official Symbol:
RGS5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
O15539
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O15539
User NOte:
Optimal dilutions for each application to be determined by the researcher.