SAR1B Antibody
| Code | Size | Price |
|---|
| PSI-55-163-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB
Application Note:
For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a small GTPase that
acts as a homodimer. The encoded protein is activated by the
guanine nucleotide exchange factor PREB and is involved in protein
transport from the endoplasmic reticulum to the Golgi. This protein
is part of the COPII coat complex. Defects in this gene are a cause
of chylomicron retention disease (CMRD), also known as Anderson
disease (ANDD). Two transcript variants encoding the same protein
have been found for this gene.
Background References:
- Cefalu, A.B., et al. Metab. Clin. Exp. 59(4):463-467(2010)
- Silvain, M., et al. Clin. Genet. 74(6):546-552(2008)
- Charcosset, M., et al. Mol. Genet. Metab. 93(1):74-84(2008)
- Jardim, D.L., et al. J. Biochem. Mol. Biol. 38(3):328-333(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse, Pig, Rat
Immunogen:
This SAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.
NCBI Gene ID #:
51128
NCBI Official Name:
GTP-binding protein SAR1b
NCBI Official Symbol:
SAR1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
Q9Y6B6
Protein GI Number:
14285769
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y6B6
User NOte:
Optimal dilutions for each application to be determined by the researcher.