ITPKB Antibody
| Code | Size | Price |
|---|
| PSI-63-442-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Inositol-trisphosphate 3-kinase B, Inositol 1,5-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, InsP 3-kinase B, ITPKB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
ITPKB regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
Background References:
- Dewaste, V., et al., Biochem. Biophys. Res. Commun. 291(2):400-405 (2002).
- Woodring, P.J., et al., J. Biol. Chem. 272(48):30447-30454 (1997).
- Erneux, C., et al., Genomics 14(2):546-547 (1992).
- Takazawa, K., et al., Biochem. J. 272(1):107-112 (1990).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ITPKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from the N-terminal region of human ITPKB.
NCBI Gene ID #:
3707
NCBI Official Name:
Inositol-trisphosphate 3-kinase B
NCBI Official Symbol:
ITPKB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
102 kDa
Protein Accession #:
P27987
Protein GI Number:
62906885
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
P27987
User NOte:
Optimal dilutions for each application to be determined by the researcher.