CLDN7 Antibody
| Code | Size | Price |
|---|
| PSI-55-071-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Claudin-7, CLDN-7, CLDN7, CEPTRL2, CPETRL2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a member of the claudin family. Claudins
are integral membrane proteins and components of tight junction
strands. Tight junction strands serve as a physical barrier to
prevent solutes and water from passing freely through the
paracellular space between epithelial or endothelial cell sheets,
and also play critical roles in maintaining cell polarity and
signal transductions. Differential expression of this gene has been
observed in different types of malignancies, including breast
cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors,
prostate cancer, lung cancer, head and neck cancers, thyroid
carcinomas, etc.. Alternatively spliced transcript variants
encoding different isoforms have been found.
Background References:
- Kojima, F., et al. Oncol. Rep. 23(4):927-931(2010)
- Rendon-Huerta, E., et al.Gastrointest Cancer 41(1):52-59(2010)
- Ouban, A., et al. Histol. Histopathol. 25(1):83-90(2010)
- Kaarteenaho, R., et al. Respir. Res. 11, 59 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CLDN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the C-terminal region of human CLDN7.
NCBI Gene ID #:
1366
NCBI Official Name:
Claudin-7
NCBI Official Symbol:
CLDN7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
O95471
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O95471
User NOte:
Optimal dilutions for each application to be determined by the researcher.