PTPN20A Antibody
| Code | Size | Price |
|---|
| PSI-56-046-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tyrosine-protein phosphatase non-receptor type 20, hPTPN20, PTPN20A
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The product of this gene belongs to the family of
classical tyrosine-specific protein tyrosine phosphatases. Many
protein tyrosine phosphatases have been shown to regulate
fundamental cellular processes and several are mutated in human
diseases. Chromosome 10q contains a segmental duplication resulting
in multiple copies of the protein tyrosine phosphatase,
non-receptor type 20 gene. The two nearly identical copies are
designated as PTPN20A and PTPN20B. A third copy is only partially
duplicated and contains a pseudogene, designated as PTPN20C. This
gene encodes the more telomeric copy, PTPN20B. Multiple
alternatively spliced transcript variants encoding different
isoforms have been identified.
Background References:
- Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
- Fodero-Tavoletti, M.T., et al. Biochem. J. 389 (PT 2), 343-354 (2005) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTPN20A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the Central region of human PTPN20A.
NCBI Gene ID #:
26095
NCBI Official Name:
Tyrosine-protein phosphatase non-receptor type 20
NCBI Official Symbol:
PTPN20A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q4JDL3
Protein GI Number:
121944218
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q4JDL3
User NOte:
Optimal dilutions for each application to be determined by the researcher.