MINPP1 Antibody

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ProSci
Product Code: PSI-55-045
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-045-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).
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MINPP1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in murine erythroleukemia cell line lysates (35ug/lane).(Kindly offered by Doc. Norma)
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Western blot analysis in K562 cell line lysates (35ug/lane).
MINPP1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in murine erythroleukemia cell line lysates (35ug/lane).(Kindly offered by Doc. Norma)

Documents

Further Information

Additional Names:
Multiple inositol polyphosphate phosphatase 1,3-bisphosphoglycerate 3-phosphatase,3-BPG phosphatase, Inositol (1,5)-tetrakisphosphate 3-phosphatase, Ins(1,5)P(4) 3-phosphatase, MINPP1, MIPP
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.
Background References:
  • Newman, A.B., et al. J. Gerontol.Biol. Sci. Med. Sci. 65(5):478-487(2010)
  • Cho, J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(16):5998-6003(2008)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This MINPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human MINPP1.
NCBI Gene ID #:
9562
NCBI Official Name:
Multiple inositol polyphosphate phosphatase 1
NCBI Official Symbol:
MINPP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q9UNW1
Protein GI Number:
68565617
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9UNW1
User NOte:
Optimal dilutions for each application to be determined by the researcher.