PIK3R5 Antibody
| Code | Size | Price |
|---|
| PSI-55-906-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Phosphoinositide 3-kinase regulatory subunit 5, PI3-kinase regulatory subunit 5, PI3-kinase p101 subunit, Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit, PtdIns-3-kinase regulatory subunit, Protein FOAP-2, PtdIns-3-kinase p101, p101-PI3K, PIK3R5
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
Receptor-regulated class I phosphoinositide 3-kinases
(PI3Ks) phosphorylate the membrane lipid phosphatidylinositol
4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn
recruits and activates cytosolic effectors involved in
proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory
subunit (Brock et al., 2003 [PubMed 12507995]).
Background References:
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Segat, L., et al. Vaccine 28(10):2201-2206(2010)
- Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
- Johnson, C., et al. Oncogene 26(49):7049-7057(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PIK3R5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 763-792 amino acids from the C-terminal region of human PIK3R5.
NCBI Gene ID #:
23533
NCBI Official Name:
Phosphoinositide 3-kinase regulatory subunit 5
NCBI Official Symbol:
PIK3R5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
97 kDa
Protein Accession #:
Q8WYR1
Protein GI Number:
74716480
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8WYR1
User NOte:
Optimal dilutions for each application to be determined by the researcher.