MPP1 Antibody
| Code | Size | Price |
|---|
| PSI-55-360-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
55 kDa erythrocyte membrane protein, p55, Membrane protein, palmitoylated 1, MPP1, DXS552E, EMP55
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
This gene encodes the prototype of the membrane-associated
guanylate kinase (MAGUK) family proteins. MAGUKs interact with the
cytoskeleton and regulate cell proliferation, signaling pathways,
and intercellular junctions. The encoded protein is an extensively
palmitoylated membrane phosphoprotein containing a PDZ domain, a
Src homology 3 (SH3) motif, and a guanylate kinase domain. This
gene product interacts with various cytoskeletal proteins and cell
junctional proteins in different tissue and cell types, and may be
involved in the regulation of cell shape, hair cell development,
neural patterning of the retina, and apico-basal polarity and tumor
suppression pathways in non-erythroid cells. Multiple transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Seo, P.S., et al. Exp. Biol. Med. (Maywood) 234(3):255-262(2009)
- Seo, P.S., et al. Biochim. Biophys. Acta 1793(2):281-289(2009)
- Gosens, I., et al. Hum. Mol. Genet. 16(16):1993-2003(2007)
- Kusunoki, H., et al. Proteins 64(3):804-807(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-327 amino acids from the Central region of human MPP1.
NCBI Gene ID #:
4354
NCBI Official Name:
55 kDa erythrocyte membrane protein
NCBI Official Symbol:
MPP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
Q00013
Protein GI Number:
1346575
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q00013
User NOte:
Optimal dilutions for each application to be determined by the researcher.