CLDN2 Antibody
Code | Size | Price |
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PSI-56-551-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Claudin-2, SP82, CLDN2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene product belongs to the claudin protein family
whose members have been identified as major integral membrane
proteins localized exclusively at tight junctions. Claudins are
expressed in an organ-specific manner and regulate tissue-specific
physiologic properties of tight junctions. This protein is
expressed in the intestine. Alternatively spliced transcript
variants with different 5' untranslated region have been found for
this gene.
Background References:
- Smith, A.J., et al. J. Acquir. Immune Defic. Syndr. 55(3):306-315(2010)
- Kojima, F., et al. Oncol. Rep. 23(4):927-931(2010)
- Szakal, D.N., et al. Virchows Arch. 456(3):245-250(2010)
- Buchert, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(6):2628-2633(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CLDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-201 amino acids from the C-terminal region of human CLDN2.
NCBI Gene ID #:
9075
NCBI Official Name:
Claudin-2
NCBI Official Symbol:
CLDN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P57739
Protein GI Number:
12229749
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P57739
User NOte:
Optimal dilutions for each application to be determined by the researcher.