CLDN2 Antibody
| Code | Size | Price |
|---|
| PSI-56-552-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Claudin-2, SP82, CLDN2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene product belongs to the claudin protein family
whose members have been identified as major integral membrane
proteins localized exclusively at tight junctions. Claudins are
expressed in an organ-specific manner and regulate tissue-specific
physiologic properties of tight junctions. This protein is
expressed in the intestine. Alternatively spliced transcript
variants with different 5' untranslated region have been found for
this gene.
Background References:
- Smith, A.J., et al. J. Acquir. Immune Defic. Syndr. 55(3):306-315(2010)
- Kojima, F., et al. Oncol. Rep. 23(4):927-931(2010)
- Szakal, D.N., et al. Virchows Arch. 456(3):245-250(2010)
- Buchert, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(6):2628-2633(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CLDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-227 amino acids from the C-terminal region of human CLDN2.
NCBI Gene ID #:
9075
NCBI Official Name:
Claudin-2
NCBI Official Symbol:
CLDN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P57739
Protein GI Number:
12229749
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P57739
User NOte:
Optimal dilutions for each application to be determined by the researcher.