MAML3 Antibody

ProSci
Product Code: PSI-62-427
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-427-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of MAML3 antibody in Hela cell line lysates (35ug/lane)
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MAML3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lymphnode followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis of MAML3 antibody in Hela cell line lysates (35ug/lane)
MAML3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lymphnode followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Mastermind-like protein 3, Mam-3, MAML3 (HGNC:16272)
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
MAML3 acts as a transcriptional coactivator for NOTCH proteins. The protein has been shown to amplify NOTCH-induced transcription of HES1.
Background References:
  • Tonon,G., Nat. Genet. 33 (2), 208-213 (2003)
  • Lin,S.E., J. Biol. Chem. 277 (52), 50612-50620 (2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MAML3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-665 amino acids from the C-terminal region of human MAML3.
NCBI Gene ID #:
55534
NCBI Official Name:
Mastermind-like protein 3
NCBI Official Symbol:
MAML3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
122 kDa
Protein Accession #:
Q96JK9
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q96JK9
User NOte:
Optimal dilutions for each application to be determined by the researcher.