RAB11FIP2 Antibody

ProSci
Product Code: PSI-61-942
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-61-942-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RAB11FIP2 antibody detected the RAB11FIP2 protein (arrow).
2 / 3
RAB11FIP2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
3 / 3

Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RAB11FIP2 antibody detected the RAB11FIP2 protein (arrow).
RAB11FIP2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Rab11 family-interacting protein 2, Rab11-FIP2, NRip11, RAB11FIP2, KIAA0941
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
RAB11FIP2 is an adapter protein that plays a role in the secretory pathway. It is thought to be important for endosome recycling and receptor-mediated endocytosis. In endosome recycling, RAB11-FIP2 regulates vesicle transport from the endosomal recycling compartment (ERC) to the plasma membrane.
Background References:
  • Wang, Z., et al. Cell 135(3):535-548(2008)
  • Utley, T.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(29):10209-10214(2008)
  • Ducharme, N.A., et al. Am. J. Physiol., Cell Physiol. 293 (3), C1059-C1072 (2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RAB11FIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the Central region of human RAB11FIP2.
NCBI Gene ID #:
22841
NCBI Official Name:
Rab11 family-interacting protein 2
NCBI Official Symbol:
RAB11FIP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q7L804
Protein GI Number:
67472131
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q7L804
User NOte:
Optimal dilutions for each application to be determined by the researcher.