COPE Antibody
Code | Size | Price |
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PSI-55-787-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP, COPE
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
The product of this gene is an epsilon subunit of coatomer
protein complex. Coatomer is a cytosolic protein complex that binds
to dilysine motifs and reversibly associates with Golgi
non-clathrin-coated vesicles. It is required for budding from Golgi
membranes, and is essential for the retrograde Golgi-to-ER
transport of dilysine-tagged proteins. Coatomer complex consists of
at least the alpha, beta, beta', gamma, delta, epsilon and zeta
subunits. Alternatively spliced transcript variants encoding
different isoforms have been identified.
Background References:
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Morikawa, R.K., et al. J. Biol. Chem. 284(39):26620-26630(2009)
- Maruyama, S., et al. Mol. Cell. Biochem. 307 (1-2), 73-82 (2008) :
- Goryachev, A.B., et al. PLoS Comput. Biol.(12), E172 (2006) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Hamster, Mouse
Immunogen:
This COPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the C-terminal region of human COPE.
NCBI Gene ID #:
11316
NCBI Official Name:
Coatomer subunit epsilon
NCBI Official Symbol:
COPE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
O14579
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O14579
User NOte:
Optimal dilutions for each application to be determined by the researcher.