COL8A2 Antibody
| Code | Size | Price |
|---|
| PSI-56-083-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Collagen alpha-2(VIII) chain, Endothelial collagen, COL8A2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
This gene encodes the alpha 2 chain of type VIII collagen.
The protein is a major component of the basement membrane of the
corneal endothelium and forms homo- or heterotrimers with alpha 1
(VIII) type collagens. Defects in this gene are associated with
Fuchs endothelial corneal dystrophy and posterior polymorphous
corneal dystrophy type 2.
Background References:
- Hemadevi, B., et al. BMC Ophthalmol 10,(2010) :
- Afshari, N.A., et al. Invest. Ophthalmol. Vis. Sci. 50(3):1093-1097(2009)
- Liskova, P., et al. BrOphthalmol 91(12):1717-1718(2007)
- Aldave, A.J., et al. Cornea 26(8):963-965(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This COL8A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the C-terminal region of human COL8A2.
NCBI Gene ID #:
1296
NCBI Official Name:
Collagen alpha-2(VIII) chain
NCBI Official Symbol:
COL8A2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
P25067
Protein GI Number:
45644957
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P25067
User NOte:
Optimal dilutions for each application to be determined by the researcher.