SOCS4 Antibody
| Code | Size | Price |
|---|
| PSI-56-075-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7, SOCS4, SOCS7
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
The protein encoded by this gene contains a SH2 domain and
a SOCS BOX domain. The protein thus belongs to the suppressor of
cytokine signaling (SOCS), also known as STAT-induced STAT
inhibitor (SSI), protein family. SOCS family members are known to
be cytokine-inducible negative regulators of cytokine signaling.
Two alternatively spliced transcript variants encoding the same
protein have been found for this gene.
Background References:
- Hu, G., et al. J. Infect. Dis. 202(1):125-135(2010)
- Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
- Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
- Sasi, W., et al. BMC Cancer 10, 178 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the Central region of human SOCS4.
NCBI Gene ID #:
122809
NCBI Official Name:
Suppressor of cytokine signaling 4
NCBI Official Symbol:
SOCS4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
Q8WXH5
Protein GI Number:
20178106
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8WXH5
User NOte:
Optimal dilutions for each application to be determined by the researcher.