NPY1R Antibody
Code | Size | Price |
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PSI-60-137-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Neuropeptide Y receptor type 1, NPY1-R, NPY1R, NPYR, NPYY1
Application Note:
For WB starting dilution is: 1:1000
Background:
Neuropeptide Y (NPY; MIM 162640) is one of the most
abundant neuropeptides in the mammalian nervous system and exhibits
a diverse range of important physiologic activities, including
effects on psychomotor activity, food intake, regulation of central
endocrine secretion, and potent vasoactive effects on the
cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have
been defined by pharmacologic criteria. NPY receptors, such as
NPY1R, have been identified in a variety of tissues, including
brain, spleen, small intestine, kidney, testis, placenta, and
aortic smooth muscle (Herzog et al., 1992 [PubMed
1321422]).
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Kim, H.Y., et al. BMB Rep 43(8):547-553(2010)
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- Naukkarinen, J., et al. PLoS Genet.(6), E1000976 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig
Immunogen:
This NPY1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human NPY1R.
NCBI Gene ID #:
4886
NCBI Official Name:
Neuropeptide Y receptor type 1
NCBI Official Symbol:
NPY1R
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
P25929
Protein GI Number:
128997
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction,Growth Factor
Swissprot #:
P25929
User NOte:
Optimal dilutions for each application to be determined by the researcher.