GPR77 Antibody
| Code | Size | Price |
|---|
| PSI-60-836-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5AR2, C5L2, GPR77
Application Note:
For WB starting dilution is: 1:1000
Background:
The anaphylatoxins C3a (see MIM 120700), C4a (see MIM
120810), and C5a are cationic fragments generated during the
complement cascade that participate in host defense. In the case of
inappropriate complement activation, anaphylatoxins may be involved
in autoimmunity and sepsis. C5L2 is coexpressed with the C5a
receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils
and may modulate C5AR activity (Gerard et al., 2005 [PubMed
16204243]).
Background References:
- Bamberg, C.E., et al. J. Biol. Chem. 285(10):7633-7644(2010)
- Cui, W., et al. Mol. Immunol. 46(16):3207-3217(2009)
- Cui, W., et al. Mol. Immunol. 46(15):3086-3098(2009)
- Scola, A.M., et al. Mol. Immunol. 46(6):1149-1162(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GPR77 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human GPR77.
NCBI Gene ID #:
27202
NCBI Official Name:
C5a anaphylatoxin chemotactic receptor 2
NCBI Official Symbol:
C5AR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
Q9P296
Protein GI Number:
20137533
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction,Growth Factor
Swissprot #:
Q9P296
User NOte:
Optimal dilutions for each application to be determined by the researcher.