FZD3 Antibody

ProSci
Product Code: PSI-60-043
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-043-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in CEM cell line lysates (35ug/lane).

Western blot analysis in CEM cell line lysates (35ug/lane).

Further Information

Additional Names:
Frizzled-3, Fz-3, hFz3, FZD3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
Background References:
  • Inkster, B., et al. Neuroimage 53(3):908-917(2010)
  • Kawano, Y., et al. Br. J. Cancer 100(7):1165-1174(2009)
  • Gregorio, S.P., et al. Psychiatry Res 165 (1-2), 1-9 (2009) :
  • Wang, H.X., et al. Mol. Hum. Reprod. 15(1):11-17(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This FZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-525 amino acids from the C-terminal region of human FZD3.
NCBI Gene ID #:
7976
NCBI Official Name:
Frizzled-3
NCBI Official Symbol:
FZD3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
Q9NPG1
Protein GI Number:
17433071
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction,Growth Factor
Swissprot #:
Q9NPG1
User NOte:
Optimal dilutions for each application to be determined by the researcher.