CMKOR1 Antibody

ProSci
Product Code: PSI-55-211
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-211-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in U251 cell line lysates (35ug/lane).
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Flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot analysis in U251 cell line lysates (35ug/lane).
Flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Further Information

Additional Names:
Atypical chemokine receptor 3, C-X-C chemokine receptor type 7, CXC-R7, CXCR-7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, RDC-1, ACKR3, CMKOR1, CXCR7, GPR159, RDC1
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
CXCR7 encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq].
Background References:
  • Berahovich, R.D., et al. J. Immunol. 185(9):5130-5139(2010)
  • Watanabe, K., et al. Arthritis Rheum. 62(11):3211-3220(2010)
  • Hattermann, K., et al. Cancer Res. 70(8):3299-3308(2010)
  • Miekus, K., et al. Folia Histochem. Cytobiol. 48(1):104-111(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CMKOR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-362 amino acids from the C-terminal region of human CMKOR1.
NCBI Gene ID #:
57007
NCBI Official Name:
Atypical chemokine receptor 3
NCBI Official Symbol:
ACKR3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
P25106
Protein GI Number:
115502380
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction,Growth Factor
Swissprot #:
P25106
User NOte:
Optimal dilutions for each application to be determined by the researcher.