PTGIR Antibody
| Code | Size | Price |
|---|
| PSI-57-726-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Prostacyclin receptor, Prostaglandin I2 receptor, PGI receptor, PGI2 receptor, Prostanoid IP receptor, PTGIR, PRIPR
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the
G-protein coupled receptor family 1 and has been shown to be a
receptor for prostacyclin. Prostacyclin, the major product of
cyclooxygenase in macrovascular endothelium, elicits a potent
vasodilation and inhibition of platelet aggregation through binding
to this receptor.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Ibrahim, S., et al. Arterioscler. Thromb. Vasc. Biol. 30(9):1802-1809(2010)
- Reid, H.M., et al. J. Biol. Chem. 285(24):18709-18726(2010)
- Muto, A., et al. Int Angiol 29 (2 SUPPL), 43-48 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTGIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of human PTGIR.
NCBI Gene ID #:
5739
NCBI Official Name:
Prostacyclin receptor
NCBI Official Symbol:
PTGIR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
P43119
Protein GI Number:
1172500
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction,Growth Factor
Swissprot #:
P43119
User NOte:
Optimal dilutions for each application to be determined by the researcher.