F2RL2 Antibody
| Code | Size | Price |
|---|
| PSI-56-323-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Proteinase-activated receptor 3, PAR-3, Coagulation factor II receptor-like 2, Thrombin receptor-like 2, F2RL2, PAR3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Coagulation factor II (thrombin) receptor-like 2 (F2RL2)
is a member of the large family of 7-transmembrane-region receptors
that couple to guanosine-nucleotide-binding proteins. F2RL2 is also
a member of the protease-activated receptor family and activated by
thrombin. F2RL2 is activated by proteolytic cleavage of its
extracellular amino terminus. The new amino terminus functions as a
tethered ligand and activates the receptor. F2RL2 is a cofactor for
F2RL3 activation by thrombin. It mediates thrombin-triggered
phosphoinositide hydrolysis and is expressed in a variety of
tissues.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Popovic, M., et al. J. Thromb. Thrombolysis 30(2):164-171(2010)
- Van Laer, L., et al. Eur. J. Hum. Genet. 18(6):685-693(2010)
- Wysoczynski, M., et al. Mol. Cancer Res. 8(5):677-690(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This F2RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human F2RL2.
NCBI Gene ID #:
2151
NCBI Official Name:
Proteinase-activated receptor 3
NCBI Official Symbol:
F2RL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
O00254
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction,Growth Factor
Swissprot #:
O00254
User NOte:
Optimal dilutions for each application to be determined by the researcher.