CXCR7 Antibody

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ProSci
Product Code: PSI-63-638
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-638-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from U-251 MG cell line, using CXCR7 Antibody at 1:1000 at each lane.
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Formalin-fixed and paraffin-embedded human testis tissue reacted with CXCR7 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of lysate from U-251 MG cell line, using CXCR7 Antibody at 1:1000 at each lane.
Formalin-fixed and paraffin-embedded human testis tissue reacted with CXCR7 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Documents

Further Information

Additional Names:
Atypical chemokine receptor 3, C-X-C chemokine receptor type 7, CXC-R7, CXCR-7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, RDC-1, ACKR3, CMKOR1, CXCR7, GPR159, RDC1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
CXCR7 is a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV).
Background References:
  • Sreedharan,S.P., et.al., Proc. Natl. Acad. Sci. U.S.A. 88 (11), 4986-4990 (1991)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CXCR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-358 amino acids from the C-terminal region of human CXCR7.
NCBI Gene ID #:
57007
NCBI Official Name:
Atypical chemokine receptor 3
NCBI Official Symbol:
ACKR3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
P25106
Protein GI Number:
115502380
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction,Growth Factor
Swissprot #:
P25106
User NOte:
Optimal dilutions for each application to be determined by the researcher.