RBBP7 Antibody
Code | Size | Price |
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PSI-58-401-400ul | 400ul | £626.00 |
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Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46
Application Note:
For WB starting dilution is: 1:1000
Background:
This protein is a ubiquitously expressed nuclear protein
and belongs to a highly conserved subfamily of WD-repeat proteins.
It is found among several proteins that binds directly to
retinoblastoma protein, which regulates cell proliferation. The
encoded protein is found in many histone deacetylase complexes,
including mSin3 co-repressor complex. It is also present in protein
complexes involved in chromatin assembly. This protein can interact
with BRCA1 tumor-suppressor gene and may have a role in the
regulation of cell proliferation and differentiation. Two
transcript variants encoding different isoforms have been found for
this gene.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Saade, E., et al. Proteomics 9(21):4934-4943(2009)
- Wang, C.L., et al. J. Proteome Res. 8(10):4428-4440(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Rat
Immunogen:
This RBBP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of human RBBP7.
NCBI Gene ID #:
5931
NCBI Official Name:
Histone-binding protein RBBP7
NCBI Official Symbol:
RBBP7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q16576
Protein GI Number:
2494891
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q16576
User NOte:
Optimal dilutions for each application to be determined by the researcher.