SAP30 Antibody

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ProSci
Product Code: PSI-58-906
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-906-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from human spleen tissue lysate, using SAP30 Antibody at 1:1000 at each lane.
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Western blot analysis of lysate from human spleen tissue lysate, using SAP30 Antibody at 1:1000 at each lane.

Documents

Further Information

Additional Names:
Histone deacetylase complex subunit SAP30, 30 kDa Sin3-associated polypeptide, Sin3 corepressor complex subunit SAP30, Sin3-associated polypeptide p30, SAP30 (HGNC:10532)
Application Note:
For WB starting dilution is: 1:1000
Background:
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq].
Background References:
  • Brandt, S., et al. Int. J. Biochem. Cell Biol. 42(9):1472-1481(2010)
  • Viiri, K.M., et al. Mol. Cell. Biol. 29(2):342-356(2009)
  • Sichtig, N., et al. Arch. Biochem. Biophys. 467(1):67-75(2007)
  • Szafranski, K., et al. Genome Biol.(8), R154 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SAP30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the C-terminal region of human SAP30.
NCBI Gene ID #:
8819
NCBI Official Name:
Histone deacetylase complex subunit SAP30
NCBI Official Symbol:
SAP30
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
O75446
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O75446
User NOte:
Optimal dilutions for each application to be determined by the researcher.