TAF6L Antibody
| Code | Size | Price |
|---|
| PSI-60-381-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L, PCAF-associated factor 65-alpha, PAF65-alpha, TAF6L, PAF65A
Application Note:
For WB starting dilution is: 1:1000
Background:
Initiation of transcription by RNA polymerase II requires
the activities of more than 70 polypeptides. The protein that
coordinates these activities is transcription factor IID (TFIID),
which binds to the core promoter to position the polymerase
properly, serves as the scaffold for assembly of the remainder of
the transcription complex, and acts as a channel for regulatory
signals. TFIID is composed of the TATA-binding protein (TBP) and a
group of evolutionarily conserved proteins known as TBP-associated
factors or TAFs. TAFs may participate in basal transcription, serve
as coactivators, function in promoter recognition or modify general
transcription factors (GTFs) to facilitate complex assembly and
transcription initiation. This gene encodes a protein that is a
component of the PCAF histone acetylase complex and structurally
similar to one of the histone-like TAFs, TAF6. The PCAF histone
acetylase complex, which is composed of more than 20 polypeptides
some of which are TAFs, is required for myogenic transcription and
differentiation.
Background References:
- Clarke, D.L., et al. J. Immunol. 181(5):3503-3514(2008)
- Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
- Lim, J., et al. Cell 125(4):801-814(2006)
- Pitkanen, J., et al. Biochem. Biophys. Res. Commun. 333(3):944-953(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TAF6L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-103 amino acids from the N-terminal region of human TAF6L.
NCBI Gene ID #:
10629
NCBI Official Name:
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L
NCBI Official Symbol:
TAF6L
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q9Y6J9
Protein GI Number:
46577572
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9Y6J9
User NOte:
Optimal dilutions for each application to be determined by the researcher.