NFYC Antibody
Code | Size | Price |
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PSI-58-221-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC, Transactivator HSM-1/2, NFYC
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes one subunit of a trimeric complex
forming a highly conserved transcription factor that binds with
high specificity to CCAAT motifs in the promoters of a variety of
genes. The encoded protein, subunit C, forms a tight dimer with the
B subunit, a prerequisite for subunit A association. The resulting
trimer binds to DNA with high specificity and affinity. Subunits B
and C each contain a histone-like motif. Multiple transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)
- Murai-Takeda, A., et al. J. Biol. Chem. 285(11):8084-8093(2010)
- Ceribelli, M., et al. J. Biol. Chem. 284(49):34189-34200(2009)
- Yamanaka, K., et al. Genomics 94(4):219-227(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This NFYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the N-terminal region of human NFYC.
NCBI Gene ID #:
4802
NCBI Official Name:
Nuclear transcription factor Y subunit gamma
NCBI Official Symbol:
NFYC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q13952
Protein GI Number:
20137773
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q13952
User NOte:
Optimal dilutions for each application to be determined by the researcher.