HIST1H2BH/HIST1H2BK/HIST3H2BB Antibody
| Code | Size | Price |
|---|
| PSI-59-972-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histone H2B type 1-H, Histone H2Bj, H2B/j, HIST1H2BH, H2BFJ
Application Note:
For WB starting dilution is: 1:1000
Background:
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene is intronless and encodes a member of the
histone H2B family. Transcripts from this gene lack polyA tails but
instead contain a palindromic termination element. This gene is
found in the large histone gene cluster on chromosome 6. [provided
by RefSeq].
Background References:
- Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)
- Beck, H.C., et al. Mol. Cell Proteomics 5(7):1314-1325(2006)
- Pavri, R., et al. Cell 125(4):703-717(2006)
- Bonenfant, D., et al. Mol. Cell Proteomics 5(3):541-552(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Xenopus, Mouse, Bovine, Chicken, Zebrafish, Rat
Immunogen:
This HIST1H2BH/HIST1H2BK/HIST3H2BB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-52 amino acids from the Central region of human HIST1H2BH/HIST1H2BK/HIST3H2BB.
NCBI Gene ID #:
8345
NCBI Official Name:
Histone H2B type 1-H
NCBI Official Symbol:
HIST1H2BH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
14 kDa
Protein Accession #:
Q93079
Protein GI Number:
7387739
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q93079
User NOte:
Optimal dilutions for each application to be determined by the researcher.