CNOT2 Antibody
| Code | Size | Price |
|---|
| PSI-57-581-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
CCR4-NOT transcription complex subunit 2, CCR4-associated factor 2, CNOT2, CDC36, NOT2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a subunit of the multi-component
CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and
degradation and is also thought to be involved in mRNA splicing,
transport and localization. The encoded protein interacts with
histone deacetylases and functions as a repressor of polymerase II
transcription. Alternatively spliced transcript variants have been
observed for this gene.
Background References:
- Lau, N.C., et al. Biochem. J. 422(3):443-453(2009)
- Miyasaka, T., et al. Cancer Sci. 99(4):755-761(2008)
- Morita, M., et al. Mol. Cell. Biol. 27(13):4980-4990(2007)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This CNOT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the Central region of human CNOT2.
NCBI Gene ID #:
4848
NCBI Official Name:
CCR4-NOT transcription complex subunit 2
NCBI Official Symbol:
CNOT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
Q9NZN8
Protein GI Number:
46396017
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NZN8
User NOte:
Optimal dilutions for each application to be determined by the researcher.