H2BFWT Antibody
| Code | Size | Price |
|---|
| PSI-58-632-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histone H2B type W-T, H2B histone family member W testis-specific, H2BFWT
Application Note:
For WB starting dilution is: 1:1000
Background:
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene encodes a member of the H2B histone family
that is specifically expressed in sperm nuclei. A polymorphism in
the 5' UTR of this gene is associated with male infertility.
Background References:
- Lee, J., et al. J. Cell. Mol. Med. 13 (8B), 1942-1951 (2009) :
- Boulard, M., et al. Mol. Cell. Biol. 26(4):1518-1526(2006)
- Churikov, D., et al. Genomics 84(4):745-756(2004)
- Churikov, D., et al. Cytogenet. Genome Res. 105 (2-4), 203-214 (2004) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This H2BFWT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-88 amino acids from the Central region of human H2BFWT.
NCBI Gene ID #:
158983
NCBI Official Name:
Histone H2B type W-T
NCBI Official Symbol:
H2BFWT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
Q7Z2G1
Protein GI Number:
223590216
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q7Z2G1
User NOte:
Optimal dilutions for each application to be determined by the researcher.