HMGB2 Antibody
| Code | Size | Price |
|---|
| PSI-62-718-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
High mobility group protein B2, High mobility group protein 2, HMG-2, HMGB2, HMG2
Application Note:
For WB starting dilution is: 1:1000
Background:
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Background References:
- Majumdar A., Brown D. 19:6643-6643(1991)
- Shirakawa H., Yoshida M.J.. 267:6641-6645(1992)
- Alexandre S., Li W.W.Nucleic Acids Res. 20:6413-6413(1992)
- Fan Z., Beresford P.J.Mol. Cell. Biol. 22:2810-2820(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Pig, Rat
Immunogen:
This HMGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-118 amino acids from the Central region of human HMGB2.
NCBI Gene ID #:
3148
NCBI Official Name:
High mobility group protein B2
NCBI Official Symbol:
HMGB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
P26583
Protein GI Number:
123374
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
P26583
User NOte:
Optimal dilutions for each application to be determined by the researcher.