EXOSC4 Antibody
| Code | Size | Price |
|---|
| PSI-59-063-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A, EXOSC4, RRP41, SKI6
Application Note:
For WB starting dilution is: 1:1000
Background:
Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. Required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity. Plays a role in replication-dependent histone mRNA degradation.
Background References:
- Mullen, T.E., et al. Genes Dev. 22(1):50-65(2008)
- van Dijk, E.L., et al. RNA 13(7):1027-1035(2007)
- Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
- Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This EXOSC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-96 amino acids from the Central region of human EXOSC4.
NCBI Gene ID #:
54512
NCBI Official Name:
Exosome complex component RRP41
NCBI Official Symbol:
EXOSC4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
Q9NPD3
Protein GI Number:
14285756
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NPD3
User NOte:
Optimal dilutions for each application to be determined by the researcher.