PAF1 Antibody
| Code | Size | Price |
|---|
| PSI-58-886-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
RNA polymerase II-associated factor 1 homolog, hPAF1, Pancreatic differentiation protein 2, PAF1, PD2
Application Note:
For WB starting dilution is: 1:1000
Background:
PAF1, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507),
and CTR9 (MIM 609366) form the PAF protein complex that associates
with the RNA polymerase II subunit POLR2A (MIM 180660) and with a
histone methyltransferase complex (Rozenblatt-Rosen et al., 2005
[PubMed 15632063]). The PAF complex also has a role in histone
monoubiquitination (Zhu et al., 2005 [PubMed 16307923]).[supplied
by OMIM].
Background References:
- Muntean, A.G., et al. Cancer Cell 17(6):609-621(2010)
- Kim, J., et al. Cell 140(4):491-503(2010)
- Moniaux, N., et al. PLoS ONE(9), E7077 (2009) :
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This PAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439-467 amino acids from the C-terminal region of human PAF1.
NCBI Gene ID #:
54623
NCBI Official Name:
RNA polymerase II-associated factor 1 homolog
NCBI Official Symbol:
PAF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
Q8N7H5
Protein GI Number:
182670295
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8N7H5
User NOte:
Optimal dilutions for each application to be determined by the researcher.