SAP130 Antibody

ProSci
Product Code: PSI-58-216
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-216-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
Histone deacetylase complex subunit SAP130, 130 kDa Sin3-associated polypeptide, Sin3-associated polypeptide p130, SAP130
Application Note:
For WB starting dilution is: 1:1000
Background:
SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Truty, M.J., et al. J. Biol. Chem. 284(10):6291-6300(2009)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
  • Fleischer, T.C., et al. Mol. Cell. Biol. 23(10):3456-3467(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen:
This SAP130 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 909-937 amino acids from the C-terminal region of human SAP130.
NCBI Gene ID #:
79595
NCBI Official Name:
Histone deacetylase complex subunit SAP130
NCBI Official Symbol:
SAP130
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
Q9H0E3
Protein GI Number:
74717977
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9H0E3
User NOte:
Optimal dilutions for each application to be determined by the researcher.